Edward J. Calabrese is a professor of toxicology at the University of Massachusetts Amherst’s School of Public Health and Health Sciences. Calabrese has done extensive research in the area of host factors affecting susceptibility to pollutants and is the author of over 750 papers in scholarly journals, as well as more than 10 books. He has been a member of the US National Academy of Sciences and NATO Countries Safe Drinking Water committees and on the Board of Scientific Counselors for the Agency for Toxic Substances and Disease Registry. Calabrese also serves as chairman of Biological Effects of Low Level Exposures and as director of the Northeast Regional Environmental Public Health Center at the University of Massachusetts.
He was awarded the 2009 Marie Curie Prize for his body of work on hormesis and is the recipient of the International Society for Cell Communication and Signaling–Springer award for 2010. He was awarded an honorary doctor of science Degree from McMaster University in 2013. His research has led to important discoveries that indicate that the most fundamental dose response in toxicology and pharmacology is the hormetic-biphasic dose response relationship. These observations are leading to a major transformation in improving drug discovery and development and in the efficiency of the clinical trial, as well as in the scientific foundations for risk assessment and environmental regulation for radiation and chemicals.